ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

CD4 T cell activation induces nuclear and cytoplasmic actin polymerization via the Arp2/3 complex to activate cytokine expression and strengthen T cell receptor (TCR) signaling. Actin polymerization dynamics and filament morphology differ between nucleus and cytoplasm. However, it is unclear how the...

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Detalles Bibliográficos
Autores principales: Sadhu, Lopamudra, Tsopoulidis, Nikolaos, Hasanuzzaman, Md, Laketa, Vibor, Way, Michael, Fackler, Oliver T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171864/
https://www.ncbi.nlm.nih.gov/pubmed/37162507
http://dx.doi.org/10.7554/eLife.82450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171864/
https://www.ncbi.nlm.nih.gov/pubmed/37162507
http://dx.doi.org/10.7554/eLife.82450

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