Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-based GLUT4 trafficking in human and mouse muscle...

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Detalles Bibliográficos
Autores principales: Knudsen, Jonas R, Persson, Kaspar W, Henriquez-Olguin, Carlos, Li, Zhencheng, Di Leo, Nicolas, Hesselager, Sofie A, Raun, Steffen H, Hingst, Janne R, Trouillon, Raphaël, Wohlwend, Martin, Wojtaszewski, Jørgen FP, Gijs, Martin AM, Jensen, Thomas Elbenhardt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171867/
https://www.ncbi.nlm.nih.gov/pubmed/37073948
http://dx.doi.org/10.7554/eLife.83338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171867/
https://www.ncbi.nlm.nih.gov/pubmed/37073948
http://dx.doi.org/10.7554/eLife.83338

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