Cargando…

Local generation and efficient evaluation of numerous drug combinations in a single sample

We develop a method that allows one to test a large number of drug combinations in a single-cell culture sample. We rely on the randomness of drug uptake in individual cells as a tool to create and encode drug treatment regimens. A single sample containing thousands of cells is treated with a combin...

Descripción completa

Detalles Bibliográficos
Autores principales: Elgart, Vlad, Loscalzo, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171870/
https://www.ncbi.nlm.nih.gov/pubmed/37039628
http://dx.doi.org/10.7554/eLife.85439