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β‐Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control

BACKGROUND: Type 2 diabetes (T2D) is characterized by a progressive deterioration of β‐cell function with a continuous decline in insulin secretion. Glucokinase (GCK) facilitates the rate‐limiting step of glycolysis in pancreatic β‐cells, to acquire the proper glucose‐stimulated insulin secretion. M...

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Detalles Bibliográficos
Autores principales: Liu, Jingwen, Fu, Hui, Kang, Fuyun, Ning, Guang, Ni, Qicheng, Wang, Weiqing, Wang, Qidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172022/
https://www.ncbi.nlm.nih.gov/pubmed/36942376
http://dx.doi.org/10.1111/1753-0407.13380