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Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena

Neprilysin (NEP) is a transmembrane zinc‐dependent metalloproteinase that inactivates various peptide hormones including glucagon‐like peptide 1 (GLP‐1). NEP inhibitors may be effective in the management of type 2 diabetes mellitus (T2DM) by increasing the circulating level of GLP‐1. However, acute‐...

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Detalles Bibliográficos
Autores principales: AlAnazi, Faisal Holil, Al‐kuraishy, Hayder M., Al‐Gareeb, Ali I., Alexiou, Athanasios, Papadakis, Marios, Ogaly, Hanan A., Alanazi, Yousef Abud, Saad, Hebatallah M., Batiha, Gaber El‐Saber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172023/
https://www.ncbi.nlm.nih.gov/pubmed/37078106
http://dx.doi.org/10.1111/1753-0407.13389