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DIGGER-Bac: prediction of seed regions for high-fidelity construction of synthetic small RNAs in bacteria

Synthetic small RNAs (sRNAs) are gaining increasing attention in the field of synthetic biology and bioengineering for efficient post-transcriptional regulation of gene expression. However, the optimal design of synthetic sRNAs is challenging because alterations may impair functions or off-target ef...

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Detalles Bibliográficos
Autores principales: Philipp, Niklas, Brinkmann, Cedric K, Georg, Jens, Schindler, Daniel, Berghoff, Bork A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172035/
https://www.ncbi.nlm.nih.gov/pubmed/37086442
http://dx.doi.org/10.1093/bioinformatics/btad285