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DIGGER-Bac: prediction of seed regions for high-fidelity construction of synthetic small RNAs in bacteria
Synthetic small RNAs (sRNAs) are gaining increasing attention in the field of synthetic biology and bioengineering for efficient post-transcriptional regulation of gene expression. However, the optimal design of synthetic sRNAs is challenging because alterations may impair functions or off-target ef...
Autores principales: | Philipp, Niklas, Brinkmann, Cedric K, Georg, Jens, Schindler, Daniel, Berghoff, Bork A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172035/ https://www.ncbi.nlm.nih.gov/pubmed/37086442 http://dx.doi.org/10.1093/bioinformatics/btad285 |
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