twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis

SUMMARY: Genome-wide association studies (GWASs) have identified numerous genetic variants associated with complex disease risk; however, most of these associations are non-coding, complicating identifying their proximal target gene. Transcriptome-wide association studies (TWASs) have been proposed...

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Detalles Bibliográficos
Autores principales: Wang, Xinran, Lu, Zeyun, Bhattacharya, Arjun, Pasaniuc, Bogdan, Mancuso, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172036/
https://www.ncbi.nlm.nih.gov/pubmed/37099718
http://dx.doi.org/10.1093/bioinformatics/btad288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172036/
https://www.ncbi.nlm.nih.gov/pubmed/37099718
http://dx.doi.org/10.1093/bioinformatics/btad288

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