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twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis
SUMMARY: Genome-wide association studies (GWASs) have identified numerous genetic variants associated with complex disease risk; however, most of these associations are non-coding, complicating identifying their proximal target gene. Transcriptome-wide association studies (TWASs) have been proposed...
Autores principales: | Wang, Xinran, Lu, Zeyun, Bhattacharya, Arjun, Pasaniuc, Bogdan, Mancuso, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172036/ https://www.ncbi.nlm.nih.gov/pubmed/37099718 http://dx.doi.org/10.1093/bioinformatics/btad288 |
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