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ICAT: a novel algorithm to robustly identify cell states following perturbations in single-cell transcriptomes
MOTIVATION: The detection of distinct cellular identities is central to the analysis of single-cell RNA sequencing (scRNA-seq) experiments. However, in perturbation experiments, current methods typically fail to correctly match cell states between conditions or erroneously remove population substruc...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172037/ https://www.ncbi.nlm.nih.gov/pubmed/37086439 http://dx.doi.org/10.1093/bioinformatics/btad278 |