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Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics

Major aims of single-cell proteomics include increasing the consistency, sensitivity and depth of protein quantification, especially for proteins and modifications of biological interest. Here, to simultaneously advance all these aims, we developed prioritized Single-Cell ProtEomics (pSCoPE). pSCoPE...

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Detalles Bibliográficos
Autores principales: Huffman, R. Gray, Leduc, Andrew, Wichmann, Christoph, Di Gioia, Marco, Borriello, Francesco, Specht, Harrison, Derks, Jason, Khan, Saad, Khoury, Luke, Emmott, Edward, Petelski, Aleksandra A., Perlman, David H., Cox, Jürgen, Zanoni, Ivan, Slavov, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172113/
https://www.ncbi.nlm.nih.gov/pubmed/37012480
http://dx.doi.org/10.1038/s41592-023-01830-1