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Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics
Major aims of single-cell proteomics include increasing the consistency, sensitivity and depth of protein quantification, especially for proteins and modifications of biological interest. Here, to simultaneously advance all these aims, we developed prioritized Single-Cell ProtEomics (pSCoPE). pSCoPE...
Autores principales: | Huffman, R. Gray, Leduc, Andrew, Wichmann, Christoph, Di Gioia, Marco, Borriello, Francesco, Specht, Harrison, Derks, Jason, Khan, Saad, Khoury, Luke, Emmott, Edward, Petelski, Aleksandra A., Perlman, David H., Cox, Jürgen, Zanoni, Ivan, Slavov, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172113/ https://www.ncbi.nlm.nih.gov/pubmed/37012480 http://dx.doi.org/10.1038/s41592-023-01830-1 |
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