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Rapid detection of neurons in widefield calcium imaging datasets after training with synthetic data

Widefield microscopy can provide optical access to multi-millimeter fields of view and thousands of neurons in mammalian brains at video rate. However, tissue scattering and background contamination results in signal deterioration, making the extraction of neuronal activity challenging, laborious an...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanlong, Zhang, Guoxun, Han, Xiaofei, Wu, Jiamin, Li, Ziwei, Li, Xinyang, Xiao, Guihua, Xie, Hao, Fang, Lu, Dai, Qionghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172132/
https://www.ncbi.nlm.nih.gov/pubmed/37002377
http://dx.doi.org/10.1038/s41592-023-01838-7