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Comparison of transformations for single-cell RNA-seq data

The count table, a numeric matrix of genes × cells, is the basic input data structure in the analysis of single-cell RNA-sequencing data. A common preprocessing step is to adjust the counts for variable sampling efficiency and to transform them so that the variance is similar across the dynamic rang...

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Detalles Bibliográficos
Autores principales: Ahlmann-Eltze, Constantin, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172138/
https://www.ncbi.nlm.nih.gov/pubmed/37037999
http://dx.doi.org/10.1038/s41592-023-01814-1