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Association between altered metabolism and genetic mutations in human glioma

BACKGROUND: Molecular markers for classification of gliomas include isocitrate dehydrogenase (IDH) mutations and codeletion of chromosomal arms 1p and 19q (1p/19q). While mutations in IDH enzymes result in the well‐characterized production of oncometabolite 2‐hydroxyglutarate, dysregulation of other...

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Detalles Bibliográficos
Autores principales: Pearl, Hannah, Fleischer, Candace C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172161/
https://www.ncbi.nlm.nih.gov/pubmed/36916606
http://dx.doi.org/10.1002/cnr2.1799