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TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway

Cisplatin resistance along with chemotherapy-induced neuropathic pain is an important cause of treatment failure for many cancer types and represents an unmet clinical need. Therefore, future studies should provide evidence regarding the mechanisms of potential targets that can overcome the resistan...

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Detalles Bibliográficos
Autores principales: Oh, Se Jin, Lim, Ji Yeon, Son, Min Kyu, Ahn, Jun Hyeok, Song, Kwon-Ho, Lee, Hyo-Jung, Kim, Suyeon, Cho, Eun Ho, Chung, Joon-Yong, Cho, Hanbyoul, Kim, Hyosun, Kim, Jae-Hoon, Park, Jooyoung, Choi, Jungmin, Hwang, Sun Wook, Kim, Tae Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172196/
https://www.ncbi.nlm.nih.gov/pubmed/37165076
http://dx.doi.org/10.1038/s41467-023-38318-7