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Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells

BCR/ABL1 causes dysregulated cell proliferation and is responsible for chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph1-ALL). In addition to the deregulatory effects of its kinase activity on cell proliferation, BCR/ABL1 induces genomic instab...

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Detalles Bibliográficos
Autores principales: Hiroki, Haruka, Ishii, Yuko, Piao, Jinhua, Namikawa, Yui, Masutani, Mitsuko, Honda, Hiroaki, Akahane, Koshi, Inukai, Takeshi, Morio, Tomohiro, Takagi, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172294/
https://www.ncbi.nlm.nih.gov/pubmed/37165001
http://dx.doi.org/10.1038/s41598-023-33852-2