Efficient production of recombinant proteins in suspension CHO cells culture using the Tol2 transposon system coupled with cycloheximide resistance selection

DNA recombination techniques in mammalian cells has been applied to the production of therapeutic proteins for several decades. To be used for commercial production, established cell lines should stably express target proteins with high productivity and acceptable quality for human use. In the conve...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Keina, Ogawa, Risa, Tsukahara, Masayoshi, Kawakami, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172305/
https://www.ncbi.nlm.nih.gov/pubmed/37165015
http://dx.doi.org/10.1038/s41598-023-34636-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172305/
https://www.ncbi.nlm.nih.gov/pubmed/37165015
http://dx.doi.org/10.1038/s41598-023-34636-4

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