Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche

Cancer immunotherapies have revolutionized treatment but have shown limited success as single-agent therapies highlighting the need to understand the origin, assembly, and dynamics of heterogeneous tumor immune niches. Here, we use single-cell and imaging-based spatial analysis to elucidate three mi...

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Detalles Bibliográficos
Autores principales: Haensel, Daniel, Daniel, Bence, Gaddam, Sadhana, Pan, Cory, Fabo, Tania, Bjelajac, Jeremy, Jussila, Anna R., Gonzalez, Fernanda, Li, Nancy Yanzhe, Chen, Yun, Hou, JinChao, Patel, Tiffany, Aasi, Sumaira, Satpathy, Ansuman T., Oro, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172319/
https://www.ncbi.nlm.nih.gov/pubmed/37164949
http://dx.doi.org/10.1038/s41467-023-37993-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172319/
https://www.ncbi.nlm.nih.gov/pubmed/37164949
http://dx.doi.org/10.1038/s41467-023-37993-w

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