Analysis and functional relevance of the chaperone TRAP-1 interactome in the metabolic regulation and mitochondrial integrity of cancer cells

The 90 kDa heat shock protein, Hsp90, functions as a cancer chaperone contributing to tumor proliferation. We have encountered the mitochondrial homolog of Hsp90, the TRAP-1, regulating mitochondrial dynamics, metabolism, and tumor metastasis. Although Hsp90 is associated with a broad network of pro...

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Detalles Bibliográficos
Autores principales: Dharaskar, Shrikant Purushottam, Paithankar, Khanderao, Amere Subbarao, Sreedhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172325/
https://www.ncbi.nlm.nih.gov/pubmed/37165028
http://dx.doi.org/10.1038/s41598-023-34728-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172325/
https://www.ncbi.nlm.nih.gov/pubmed/37165028
http://dx.doi.org/10.1038/s41598-023-34728-1

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