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Analysis and functional relevance of the chaperone TRAP-1 interactome in the metabolic regulation and mitochondrial integrity of cancer cells
The 90 kDa heat shock protein, Hsp90, functions as a cancer chaperone contributing to tumor proliferation. We have encountered the mitochondrial homolog of Hsp90, the TRAP-1, regulating mitochondrial dynamics, metabolism, and tumor metastasis. Although Hsp90 is associated with a broad network of pro...
Autores principales: | Dharaskar, Shrikant Purushottam, Paithankar, Khanderao, Amere Subbarao, Sreedhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172325/ https://www.ncbi.nlm.nih.gov/pubmed/37165028 http://dx.doi.org/10.1038/s41598-023-34728-1 |
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