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Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease

BACKGROUND: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling the search for protein biomarkers for early detection of th...

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Detalles Bibliográficos
Autores principales: Hadisurya, Marco, Li, Li, Kuwaranancharoen, Kananart, Wu, Xiaofeng, Lee, Zheng-Chi, Alcalay, Roy N., Padmanabhan, Shalini, Tao, W. Andy, Iliuk, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172329/
https://www.ncbi.nlm.nih.gov/pubmed/37165152
http://dx.doi.org/10.1038/s43856-023-00294-w