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Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder

Preliminary clinical findings, supported by preclinical studies employing behavioral paradigms such as marble burying, suggest that psilocybin may be effective in treating obsessive-compulsive disorder. However, the receptor mechanisms implicated in the putative anti-obsessional effect are not clear...

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Detalles Bibliográficos
Autores principales: Singh, Sandeep, Botvinnik, Alexander, Shahar, Orr, Wolf, Gilly, Yakobi, Corel, Saban, Michal, Salama, Adham, Lotan, Amit, Lerer, Bernard, Lifschytz, Tzuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172379/
https://www.ncbi.nlm.nih.gov/pubmed/37164956
http://dx.doi.org/10.1038/s41398-023-02456-9