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Disease-causing mutations in genes encoding transcription factors critical for photoreceptor development
Photoreceptor development of the vertebrate visual system is controlled by a complex transcription regulatory network. OTX2 is expressed in the mitotic retinal progenitor cells (RPCs) and controls photoreceptor genesis. CRX that is activated by OTX2 is expressed in photoreceptor precursors after cel...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172487/ https://www.ncbi.nlm.nih.gov/pubmed/37181651 http://dx.doi.org/10.3389/fnmol.2023.1134839 |