Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy

Introduction: The endothelial glycocalyx degrading enzyme heparanase-1 (HPSE1) is a major contributor to kidney diseases, such as glomerulonephritis and diabetic nephropathy. Therefore, inhibition of HPSE1 could be an interesting therapeutic strategy to treat glomerular diseases. A possible HPSE1 in...

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Detalles Bibliográficos
Autores principales: Buijsers, Baranca, Garsen, Marjolein, de Graaf, Mark, Bakker-van Bebber, Marinka, Guo, Chunming, Li, Xue, van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172501/
https://www.ncbi.nlm.nih.gov/pubmed/37180718
http://dx.doi.org/10.3389/fphar.2023.1098184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172501/
https://www.ncbi.nlm.nih.gov/pubmed/37180718
http://dx.doi.org/10.3389/fphar.2023.1098184

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