Integrative single-cell RNA sequencing and metabolomics decipher the imbalanced lipid-metabolism in maladaptive immune responses during sepsis

BACKGROUND: To identify differentially expressed lipid metabolism-related genes (DE-LMRGs) responsible for immune dysfunction in sepsis. METHODS: The lipid metabolism-related hub genes were screened using machine learning algorithms, and the immune cell infiltration of these hub genes were assessed...

Descripción completa

Detalles Bibliográficos
Autores principales: She, Han, Tan, Lei, Wang, Yi, Du, Yuanlin, Zhou, Yuanqun, Zhang, Jun, Du, Yunxia, Guo, Ningke, Wu, Zhengbin, Li, Qinghui, Bao, Daiqin, Mao, Qingxiang, Hu, Yi, Liu, Liangming, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172510/
https://www.ncbi.nlm.nih.gov/pubmed/37180171
http://dx.doi.org/10.3389/fimmu.2023.1181697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172510/
https://www.ncbi.nlm.nih.gov/pubmed/37180171
http://dx.doi.org/10.3389/fimmu.2023.1181697

Ejemplares similares