Cargando…

FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways

BACKGROUND: Mutations in the receptor tyrosine kinase gene fibroblast growth factor receptor 2 (FGFR2) occur at a high frequency in endometrial cancer (EC) and have been linked to advanced and recurrent disease. However, little is known about how these mutations drive carcinogenesis. METHODS: Differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Dixit, Garima, Gonzalez‐Bosquet, Jesus, Skurski, Joseph, Devor, Eric J., Dickerson, Erin B., Nothnick, Warren B., Issuree, Priya D., Leslie, Kimberly K., Maretzky, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172618/
https://www.ncbi.nlm.nih.gov/pubmed/37165578
http://dx.doi.org/10.1002/ctm2.1223