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Leveraging the tolerogenic potential of TNF-α and regulatory B cells in organ transplantation

A subset of B-cells with tolerogenic functions, termed B-regulatory cells or Bregs, is characterized by the expression of anti-inflammatory/tolerogenic cytokines, namely IL-10, TGF-β, and IL-35, that contribute to their regulatory functions. Breg regulation favors graft acceptance within a tolerogen...

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Detalles Bibliográficos
Autores principales: Poznansky, Sonya A., Yu, Matthew, Deng, Kevin, Fu, Qiang, Markmann, James F., LeGuern, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172648/
https://www.ncbi.nlm.nih.gov/pubmed/37180165
http://dx.doi.org/10.3389/fimmu.2023.1173672