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Leveraging the tolerogenic potential of TNF-α and regulatory B cells in organ transplantation
A subset of B-cells with tolerogenic functions, termed B-regulatory cells or Bregs, is characterized by the expression of anti-inflammatory/tolerogenic cytokines, namely IL-10, TGF-β, and IL-35, that contribute to their regulatory functions. Breg regulation favors graft acceptance within a tolerogen...
Autores principales: | Poznansky, Sonya A., Yu, Matthew, Deng, Kevin, Fu, Qiang, Markmann, James F., LeGuern, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172648/ https://www.ncbi.nlm.nih.gov/pubmed/37180165 http://dx.doi.org/10.3389/fimmu.2023.1173672 |
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