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Improving levodopa delivery: IPX203, a novel extended-release carbidopa-levodopa formulation

INTRODUCTION: IPX203 is a novel oral extended-release (ER) formulation of carbidopa (CD) and levodopa (LD) developed to address the short half-life and limited area for absorption of LD in the gastrointestinal tract. This paper presents the formulation strategy of IPX203 and its relationship to the...

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Detalles Bibliográficos
Autores principales: LeWitt, Peter, Ellenbogen, Aaron, Burdick, Daniel, Gunzler, Steven, Gil, Ramon, Dhall, Rohit, Banisadr, Ghazal, D'Souza, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172697/
https://www.ncbi.nlm.nih.gov/pubmed/37181100
http://dx.doi.org/10.1016/j.prdoa.2023.100197