Hemoglobin resident in the lung epithelium is protective for smooth muscle soluble guanylate cyclase function

Hemoglobin (Hb) present in the lung epithelium is of unknown significance. However Hb being an nitric oxide (NO) scavenger can bind to NO and reduce its deleterious effects. Hence we postulated an NO scavenging role for this lung Hb. Doing transwell co-culture with bronchial epithelial cells, A549/1...

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Detalles Bibliográficos
Autores principales: Sumi, Mamta P., Tupta, Blair, Roychowdhury, Sanjoy, Comhair, Suzy, Asosingh, Kewal, Stuehr, Dennis J., Erzurum, Serpil C., Ghosh, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172757/
https://www.ncbi.nlm.nih.gov/pubmed/37120930
http://dx.doi.org/10.1016/j.redox.2023.102717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172757/
https://www.ncbi.nlm.nih.gov/pubmed/37120930
http://dx.doi.org/10.1016/j.redox.2023.102717

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