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Cohesin SMC1β promotes closed chromatin and controls TERRA expression at spermatocyte telomeres

Previous data showed that meiotic cohesin SMC1β protects spermatocyte telomeres from damage. The underlying reason, however, remained unknown as the expressions of telomerase and shelterin components were normal in Smc1β(−/−) spermatocytes. Here. we report that SMC1β restricts expression of the long...

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Detalles Bibliográficos
Autores principales: Biswas, Uddipta, Deb Mallik, Tanaya, Pschirer, Johannes, Lesche, Matthias, Sameith, Katrin, Jessberger, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172765/
https://www.ncbi.nlm.nih.gov/pubmed/37160312
http://dx.doi.org/10.26508/lsa.202201798