Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish

The unfolded protein response is triggered in vertebrates by ubiquitously expressed IRE1α/β (although IRE1β is gut-specific in mice), PERK, and ATF6α/β, transmembrane-type sensor proteins in the ER, to cope with ER stress, the accumulation of unfolded and misfolded proteins in the ER. Here, we burde...

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Detalles Bibliográficos
Autores principales: Jin, Byungseok, Ishikawa, Tokiro, Kashima, Makoto, Komura, Rei, Hirata, Hiromi, Okada, Tetsuya, Mori, Kazutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172766/
https://www.ncbi.nlm.nih.gov/pubmed/37160311
http://dx.doi.org/10.26508/lsa.202201771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172766/
https://www.ncbi.nlm.nih.gov/pubmed/37160311
http://dx.doi.org/10.26508/lsa.202201771

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