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Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish
The unfolded protein response is triggered in vertebrates by ubiquitously expressed IRE1α/β (although IRE1β is gut-specific in mice), PERK, and ATF6α/β, transmembrane-type sensor proteins in the ER, to cope with ER stress, the accumulation of unfolded and misfolded proteins in the ER. Here, we burde...
Autores principales: | Jin, Byungseok, Ishikawa, Tokiro, Kashima, Makoto, Komura, Rei, Hirata, Hiromi, Okada, Tetsuya, Mori, Kazutoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172766/ https://www.ncbi.nlm.nih.gov/pubmed/37160311 http://dx.doi.org/10.26508/lsa.202201771 |
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