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MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain

Pain is the hallmark symptom of osteoarthritis (OA), and current analgesic treatments may be insufficient or have potentially adverse effects. The inhibition of Monoacylglycerol lipase (MAGL) produces anti-inflammatory and anti-nociceptive effects. However, the potential mechanism of MAGL in OA pain...

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Detalles Bibliográficos
Autores principales: Gu, Chengyong, Chen, Mo, Li, Xueyan, Geng, Dechun, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172810/
https://www.ncbi.nlm.nih.gov/pubmed/37144506
http://dx.doi.org/10.3892/mmr.2023.13004