A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation

Thrombin generation (TG) assays serve as a valuable tool to study the amplifying roles of intrinsic pathway factors in human coagulation and provide functional insights into the increased bleeding observed in individuals deficient in factors (F) XI, IX, or VIII. Mice are used extensively in hemostas...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Jun, Tanratana, Pansakorn, Roest, Mark, Gruber, Andras, Pawlinski, Rafal, Wolberg, Alisa S., Mackman, Nigel, Grover, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172872/
https://www.ncbi.nlm.nih.gov/pubmed/36583671
http://dx.doi.org/10.1182/bloodadvances.2022008720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172872/
https://www.ncbi.nlm.nih.gov/pubmed/36583671
http://dx.doi.org/10.1182/bloodadvances.2022008720

Ejemplares similares