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A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo

Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding capillary network often lead to transplantation failure. Herein, a novel bioartificial pancreas is constructed via islet...

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Detalles Bibliográficos
Autores principales: Li, Haofei, Shang, Yulian, Feng, Qi, Liu, Yang, Chen, Junlin, Dong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172916/
https://www.ncbi.nlm.nih.gov/pubmed/37180642
http://dx.doi.org/10.1016/j.bioactmat.2023.04.011