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Acetylation of p65(Lys310) by p300 in macrophages mediates anti-inflammatory property of berberine

Nuclear factor (NF)-κB plays a pivotal role in the regulation of inflammatory response in macrophages. Berberine (BBR), which is an active constituent isolated from Coptis rhizome, possesses a prominent anti-inflammatory activity. Here we show that BBR changes the global acetylation landscape in LPS...

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Detalles Bibliográficos
Autores principales: Zhang, Shuchen, Xu, Pingyuan, Zhu, Ziwei, Zhou, Lingyan, Li, Jiao, Zhou, Ruonan, Kan, Yue, Li, Yaru, Yu, Xizhong, Zhao, Juan, Jin, Yu, Yan, Jing, Fang, Penghua, Shang, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172918/
https://www.ncbi.nlm.nih.gov/pubmed/37086629
http://dx.doi.org/10.1016/j.redox.2023.102704