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Metastatic breast tumors downregulate miR-145 regulating the hypoxia-induced vasculogenic mimicry

Tumor cells grow in three-dimensional (3D) channels-like structures denoted as vasculogenic mimicry (VM), which provides a route for nutrients and oxygen acquisition. VM is activated by hypoxia and associated with metastasis and poor prognosis. MetastamiRs are microRNAs regulating metastasis, howeve...

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Detalles Bibliográficos
Autores principales: Contreras-Sanzón, Estefania, Carlos-Reyes, Ángeles, Sierra-Martínez, Mónica, Acosta-Altamirano, Gustavo, Luna-Rivero, Cesar, Núñez-Corona, David, García-Hernández, Alejandra Paola, Ibarra-Sierra, Eloisa, Vidrio-Morgado, Horacio, Alvarez-Sánchez, María Elizbeth, Marchat, Laurence A., López-Camarillo, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172997/
https://www.ncbi.nlm.nih.gov/pubmed/37121177
http://dx.doi.org/10.1016/j.tranon.2023.101680