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TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoid malignancies associated with poor prognosis due to ineffective treatment options and high rates of relapse. The success of chimeric antigen receptor T-cell (CART) therapy for certain hematologic malignancies makes it an attrac...

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Detalles Bibliográficos
Autores principales: Shaw, Lauren C., Poussin, Mathilde, Rodriguez-Garcia, Alba, Eggold, Joshua, Minutolo, Nicholas G., Wang, Jie, Rook, Alain H., Schuster, Stephen J., Powell, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173171/
https://www.ncbi.nlm.nih.gov/pubmed/36053778
http://dx.doi.org/10.1182/bloodadvances.2022008798