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KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy

BACKGROUND: T cells and natural killer (NK) cells are essential components of the immune system and are regulated by coinhibitory and costimulatory molecules in which the B7 family and CD28 family play significant roles. Previous immune checkpoint studies on B7/CD28 family members, such as PD-1, hav...

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Detalles Bibliográficos
Autores principales: Li, Yang, Lv, Chao, Yu, Yang, Wu, Baokang, Zhang, Yizhou, Lang, Qi, Liang, Zhiyun, Zhong, Chongli, Shi, Yu, Han, Shukun, Xu, Feng, Tian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173190/
https://www.ncbi.nlm.nih.gov/pubmed/35933091
http://dx.doi.org/10.1016/j.jare.2022.07.013