Chromatographic Analysis of the N-Glycan Profile on Therapeutic Antibodies Using FcγRIIIa Affinity Column Chromatography

[Image: see text] N-Linked glycosylation on IgG has a profound impact on antibody functions. The relationship between the N-glycan structure and the binding affinity of FcγRIIIa, relating to antibody-dependent cell-mediated cytotoxicity (ADCC) activity, is important for the efficient development of...

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Detalles Bibliográficos
Autores principales: Hiranyakorn, Methanee, Iwamoto, Shogo, Hoshinoo, Asako, Tsumura, Ryo, Takashima, Hiroki, Yasunaga, Masahiro, Manabe, Shino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173337/
https://www.ncbi.nlm.nih.gov/pubmed/37179638
http://dx.doi.org/10.1021/acsomega.3c02374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173337/
https://www.ncbi.nlm.nih.gov/pubmed/37179638
http://dx.doi.org/10.1021/acsomega.3c02374

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