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Chromatographic Analysis of the N-Glycan Profile on Therapeutic Antibodies Using FcγRIIIa Affinity Column Chromatography

[Image: see text] N-Linked glycosylation on IgG has a profound impact on antibody functions. The relationship between the N-glycan structure and the binding affinity of FcγRIIIa, relating to antibody-dependent cell-mediated cytotoxicity (ADCC) activity, is important for the efficient development of...

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Detalles Bibliográficos
Autores principales:	Hiranyakorn, Methanee, Iwamoto, Shogo, Hoshinoo, Asako, Tsumura, Ryo, Takashima, Hiroki, Yasunaga, Masahiro, Manabe, Shino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173337/ https://www.ncbi.nlm.nih.gov/pubmed/37179638 http://dx.doi.org/10.1021/acsomega.3c02374

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