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Gastrointestinal pan-cancer landscape of tumor matrix heterogeneity identifies biologically distinct matrix stiffness subtypes predicting prognosis and chemotherapy efficacy

Gastrointestinal (GI) cancers are a heterogeneous group of primary solid tumors, arising in GI tract from the esophagus to rectum. Matrix stiffness (MS) is a critical physical factor for cancer progression; however, its importance in tumor progression remains to be comprehensively recognized. Herein...

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Detalles Bibliográficos
Autores principales: Ning, Yumei, Lin, Kun, Fang, Jun, Ding, Yang, Zhang, Zhang, Chen, Xiaojia, Zhao, Qiu, Wang, Haizhou, Wang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173364/
https://www.ncbi.nlm.nih.gov/pubmed/37181656
http://dx.doi.org/10.1016/j.csbj.2023.04.016