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VNN1 overexpression in pancreatic cancer cells inhibits paraneoplastic islet function by increasing oxidative stress and inducing β‑cell dedifferentiation

Vanin-1 (VNN1) may be a potential biomarker for the early screening of pancreatic cancer (PC)-associated diabetes (PCAD). A previous study by the authors reported that cysteamine secreted by VNN1-overexpressing PC cells induced the dysfunction of paraneoplastic insulinoma cell lines by increasing ox...

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Detalles Bibliográficos
Autores principales: Qin, Wenjie, Kang, Muxing, Li, Chao, Zheng, Wen, Guo, Qingqu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173380/
https://www.ncbi.nlm.nih.gov/pubmed/37114564
http://dx.doi.org/10.3892/or.2023.8557