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Preparation and characterization of naproxen solid dispersion using different hydrophilic carriers and in-vivo evaluation of its analgesic activity in mice

BACKGROUND: Solid dispersion (SD) has been used conventionally as a successful technique for improving the dissolution profile and bioavailability of poorly water-soluble drugs. The aim of this study was to progress the dissolution rate and bioavailability of naproxen (BCS class II) by SD technique....

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Detalles Bibliográficos
Autores principales: Nupur, Monia Akter, Rahman, Mst Mahfuza, Akter, Khurshida, Hanif, Khadiza Binte, Sharna, Jinat Fatema, Sarker, Md Shahin, Ibne Wahed, Mir Imam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173407/
https://www.ncbi.nlm.nih.gov/pubmed/37180918
http://dx.doi.org/10.1016/j.heliyon.2023.e15432