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Role of abnormal glycosylated IgA1 and interstitial transformation of glomerular endothelial cells in the development and progression of IgA nephropathy

BACKGROUND: IgA nephropathy (IgAN) is a common primary renal disease in childhood. METHODS: Twenty blood samples and renal tissue from patients with IgAN, 20 blood samples from healthy children and 10 normal renal tissue were collected. Serum Gd-IgA1 and renal Gd-IgA1, CD31, α-SMA and vimentin were...

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Detalles Bibliográficos
Autores principales: Jia, Wanyu, Dou, Wenjie, Wang, Qin, Zeng, Huiqin, Shi, Peipei, Liu, Jing, Liu, Zhen, Zhang, Jin, Zhang, Jian-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173471/
https://www.ncbi.nlm.nih.gov/pubmed/37170272
http://dx.doi.org/10.1186/s13052-023-01468-x