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A pumpless monolayer microfluidic device based on mesenchymal stem cell-conditioned medium promotes neonatal mouse in vitro spermatogenesis

BACKGROUND: Childhood cancer treatment-induced gonadotoxicity causes permanent infertility/sub-infertility in nearly half of males. The current clinical and experimental approaches are limited to cryopreservation of prepubertal testicular strips and in vitro spermatogenesis which are inadequate to a...

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Detalles Bibliográficos
Autores principales: Önen, Selin, Atik, Ali Can, Gizer, Merve, Köse, Sevil, Yaman, Önder, Külah, Haluk, Korkusuz, Petek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173473/
https://www.ncbi.nlm.nih.gov/pubmed/37170113
http://dx.doi.org/10.1186/s13287-023-03356-x