Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice

BACKGROUD: The frequencies of morbidity and impairment associated with spontaneous intracerebral haemorrhage (ICH) are comparatively high. Blood-brain barrier (BBB) integrity was compromised due to subsequent brain injury induced by ICH, which is crucial for a poor prognosis. Polymorphonuclear leuko...

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Detalles Bibliográficos
Autores principales: Gao, Ling, Peng, Li, Sherchan, Prativa, Tang, Hong, Liu, Yu, Xiao, Jie, Shi, Hui, Luo, Yujie, Tang, Jiping, Zhang, John H., Xia, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173532/
https://www.ncbi.nlm.nih.gov/pubmed/37165450
http://dx.doi.org/10.1186/s12987-023-00434-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173532/
https://www.ncbi.nlm.nih.gov/pubmed/37165450
http://dx.doi.org/10.1186/s12987-023-00434-3

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