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Descending serotonergic modulation from rostral ventromedial medulla to spinal trigeminal nucleus is involved in experimental occlusal interference-induced chronic orofacial hyperalgesia

BACKGROUND: Dental treatment associated with unadaptable occlusal alteration can cause chronic primary myofascial orofacial pain. The serotonin (5-HT) pathway from the rostral ventromedial medulla (RVM) exerts descending modulation on nociceptive transmission in the spinal trigeminal nucleus (Sp5) a...

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Detalles Bibliográficos
Autores principales: Mo, Si-Yi, Xue, Yang, Li, Yuan, Zhang, Yao-Jun, Xu, Xiao-Xiang, Fu, Kai-Yuan, Sessle, Barry J., Xie, Qiu-Fei, Cao, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173589/
https://www.ncbi.nlm.nih.gov/pubmed/37165344
http://dx.doi.org/10.1186/s10194-023-01584-3